Cytological grading of canine mast cell tumors: correlation with histologic grading and survival time

ABSTRACT: Mast cell tumors are one of the most common neoplasia in dogs and cytopathology and/or histopathology examinations used for diagnosis. Histologic grading is considered gold standard test to predict prognosis this neoplasia. However, studies have been conducted using cytological system provide similar information a faster, less invasive, more accessible way. This study aimed investigate graduation correlate it with histological survival time diagnosed cutaneous mast at Veterinary Hospital “Universidade Federal de Uberlândia” over five years. For that, slides from 72 animals were reviewed. The statistical methods kappa agreement between systems, Kaplan-Meier time, Cox regression comparison grades time. when compared two-tier histologic grading, high low grades, had moderate (kappa 0.566). When correlation grade was evaluated, there higher death rate group high-grade grade, pointing (p=0.009). In conclusion, useful treatment planning providing prognostic that precedes tumor removal, showing good animals.